GHK-Cu (Copper) Peptide Overview

GHK-Cu is a naturally occurring copper-binding tripeptide (glycyl-L-histidyl-L-lysine) found in plasma. It is typically released at the time of injury, though its concentration declines significantly with age. Research suggests it may reset elements of the human genome to a healthier state, potentially restoring impaired cells.

Chemical Makeup & Specifications

• Molecular Formula: C14H23CuN6O4
• Molecular Weight: 340.38 g/mol
• Other Names: glycyl-L-histidyl-L-lysine-copper 2+

Research and Clinical Studies

• Tissue Repair & Wound Healing: Studies suggest GHK-Cu stimulates collagen synthesis and increases protein and DNA accumulation at injury sites. In rabbit models, it appeared to exhibit increased healing compared to zinc oxide and showed synergistic effects when used with helium-neon lasers.
• Skin & Hair Health: It has been researched for its potential to tighten aging skin, restore the skin barrier, improve texture/hyperpigmentation, and increase hair follicle size.
• Metastasis & Cancer Research: Preliminary studies involving mice with sarcoma cells suggested that a mixture of GHK-Cu and Vitamin C could inhibit tumor growth and potentially reactivate apoptosis (programmed cell death) pathways.
• Diabetic Ulcers: A clinical trial using a GHK-Cu gel on diabetic subjects with neuropathic ulcers reported a healing rate of over 98%, significantly higher than the placebo group.
• Behavioral Properties: Animal studies indicate potential for pain mitigation, anxiety reduction, and a decrease in aggressive-defensive behavior following electric shocks.
• Antioxidant & Anti-inflammatory Actions:
  • Antioxidant: May target and neutralize hydroxyl and peroxyl radicals more proficiently than other antioxidants like carnosine.
  • Lung Health: Research suggests it may attenuate lung inflammation induced by cigarette smoke by interacting with the NF-κB and Nrf2 signaling pathways.
  • Lipid Peroxidation: May reduce cell damage by inhibiting the release of iron from ferritin, thereby decreasing oxidative stress.

Note: This product is sold by Republic One Labs for research and laboratory purposes only and is not intended for human consumption.